node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO76560.1 | ACO76562.1 | Avin_03000 | Avin_03020 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Conserved hypothetical protein. | 0.622 |
ACO76560.1 | ACO76568.1 | Avin_03000 | Avin_03080 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.722 |
ACO76560.1 | metW | Avin_03000 | Avin_03030 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Methionine biosynthesis protein MetW. | 0.524 |
ACO76560.1 | metX | Avin_03000 | Avin_03040 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.519 |
ACO76560.1 | proC | Avin_03000 | Avin_03070 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Delta 1-pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.617 |
ACO76560.1 | rdgB | Avin_03000 | Avin_03010 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.825 |
ACO76562.1 | ACO76560.1 | Avin_03020 | Avin_03000 | Conserved hypothetical protein. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.622 |
ACO76562.1 | ACO76565.1 | Avin_03020 | Avin_03050 | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the UPF0235 family. | 0.470 |
ACO76562.1 | ACO76566.1 | Avin_03020 | Avin_03060 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.558 |
ACO76562.1 | ACO76568.1 | Avin_03020 | Avin_03080 | Conserved hypothetical protein. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.444 |
ACO76562.1 | metW | Avin_03020 | Avin_03030 | Conserved hypothetical protein. | Methionine biosynthesis protein MetW. | 0.894 |
ACO76562.1 | metX | Avin_03020 | Avin_03040 | Conserved hypothetical protein. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.650 |
ACO76562.1 | proC | Avin_03020 | Avin_03070 | Conserved hypothetical protein. | Delta 1-pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.460 |
ACO76562.1 | rdgB | Avin_03020 | Avin_03010 | Conserved hypothetical protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.901 |
ACO76565.1 | ACO76562.1 | Avin_03050 | Avin_03020 | Conserved hypothetical protein; Belongs to the UPF0235 family. | Conserved hypothetical protein. | 0.470 |
ACO76565.1 | ACO76566.1 | Avin_03050 | Avin_03060 | Conserved hypothetical protein; Belongs to the UPF0235 family. | Conserved hypothetical protein. | 0.874 |
ACO76565.1 | ACO76568.1 | Avin_03050 | Avin_03080 | Conserved hypothetical protein; Belongs to the UPF0235 family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.809 |
ACO76565.1 | metW | Avin_03050 | Avin_03030 | Conserved hypothetical protein; Belongs to the UPF0235 family. | Methionine biosynthesis protein MetW. | 0.555 |
ACO76565.1 | metX | Avin_03050 | Avin_03040 | Conserved hypothetical protein; Belongs to the UPF0235 family. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.555 |
ACO76565.1 | pilT | Avin_03050 | Avin_03090 | Conserved hypothetical protein; Belongs to the UPF0235 family. | Pilus retraction protein. | 0.565 |