node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO77509.1 | kdsA | Avin_12830 | Avin_24680 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.982 |
ACO77509.1 | kdsA-2 | Avin_12830 | Avin_38800 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.985 |
ACO77509.1 | kdsB | Avin_12830 | Avin_14780 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.981 |
ACO77509.1 | kpsF | Avin_12830 | Avin_12840 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | Arabinose 5-phosphate isomerase protein. | 0.995 |
ACO77509.1 | lptA | Avin_12830 | Avin_12810 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | LPS transport protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.838 |
ACO77509.1 | lptB | Avin_12830 | Avin_12800 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | LPS transport protein LptB. | 0.903 |
ACO77509.1 | lptC | Avin_12830 | Avin_12820 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. | 0.905 |
ACO77509.1 | lpxB | Avin_12830 | Avin_38860 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.701 |
ACO77509.1 | lpxC | Avin_12830 | Avin_13320 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.728 |
ACO77509.1 | lpxD | Avin_12830 | Avin_38890 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.709 |
kdsA | ACO77509.1 | Avin_24680 | Avin_12830 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.982 |
kdsA | kdsA-2 | Avin_24680 | Avin_38800 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.910 |
kdsA | kdsB | Avin_24680 | Avin_14780 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.822 |
kdsA | kpsF | Avin_24680 | Avin_12840 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | Arabinose 5-phosphate isomerase protein. | 0.989 |
kdsA | lptB | Avin_24680 | Avin_12800 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | LPS transport protein LptB. | 0.494 |
kdsA | lpxB | Avin_24680 | Avin_38860 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.806 |
kdsA | lpxC | Avin_24680 | Avin_13320 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.814 |
kdsA | lpxD | Avin_24680 | Avin_38890 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.800 |
kdsA-2 | ACO77509.1 | Avin_38800 | Avin_12830 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.985 |
kdsA-2 | kdsA | Avin_38800 | Avin_24680 | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.910 |