node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO78471.1 | panC | Avin_22800 | Avin_42720 | Aminotransferase class-III protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.914 |
ACO78471.1 | panD | Avin_22800 | Avin_42730 | Aminotransferase class-III protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.916 |
ACO80671.1 | apbA | Avin_45590 | Avin_13400 | Conserved hypothetical protein. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.930 |
ACO80671.1 | panB | Avin_45590 | Avin_42710 | Conserved hypothetical protein. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.912 |
ACO80671.1 | panB-2 | Avin_45590 | Avin_46440 | Conserved hypothetical protein. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.912 |
ACO80671.1 | panC | Avin_45590 | Avin_42720 | Conserved hypothetical protein. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.916 |
apbA | ACO80671.1 | Avin_13400 | Avin_45590 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Conserved hypothetical protein. | 0.930 |
apbA | panB | Avin_13400 | Avin_42710 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.928 |
apbA | panB-2 | Avin_13400 | Avin_46440 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.924 |
apbA | panC | Avin_13400 | Avin_42720 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.927 |
cmk | panC | Avin_15860 | Avin_42720 | Cytidylate kinase. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.910 |
coaBC | coaX | Avin_02930 | Avin_06060 | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.933 |
coaBC | panB-2 | Avin_02930 | Avin_46440 | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.416 |
coaBC | panC | Avin_02930 | Avin_42720 | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.903 |
coaX | coaBC | Avin_06060 | Avin_02930 | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.933 |
coaX | panC | Avin_06060 | Avin_42720 | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.969 |
coaX | panD | Avin_06060 | Avin_42730 | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.727 |
folK | panB | Avin_42700 | Avin_42710 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; FolK. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.717 |
folK | panC | Avin_42700 | Avin_42720 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; FolK. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.742 |
folK | panD | Avin_42700 | Avin_42730 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; FolK. | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.455 |