STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crpCatabolite gene activator, c-AMP receptor protein; Crp/Vfr. (215 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor, sigma70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.874
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.855
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.850
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.838
rpoZ
DNA-directed RNA polymerase, omega subunit, RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.828
cyaB
Adenylate cyclase protein.
 
 0.774
cpdA
Cyclic 3,5-nucleotide monophosphate metallophosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
   
 0.602
ACO79672.1
Integral membrane sensor hybrid histidine protein kinase.
  
 
 0.567
ACO81151.1
Periplasmic hybrid histidine protein kinase, two-component.
   
 
 0.565
ompR
Two-component response regulator OmpR.
   
 
 0.521
Your Current Organism:
Azotobacter vinelandii
NCBI taxonomy Id: 322710
Other names: A. vinelandii DJ, Azotobacter vinelandii DJ, Azotobacter vinelandii str. DJ, Azotobacter vinelandii strain DJ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.