Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Nham_1997UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1110 aa)    
Predicted Functional Partners:
Nham_1996
Conserved hypothetical protein.
 
 
 0.996
recD2
Helicase RecD/TraA; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 0.855
Nham_3707
ATPase.
 
 
 0.760
Nham_0136
Hypothetical protein.
  
 
 0.698
Nham_0596
Conserved hypothetical protein.
  
 
 0.698
Nham_0686
Exodeoxyribonuclease V.
  
 
 0.698
pheT
phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.520
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.498
Nham_0160
DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada / transcriptional regulator, AraC family.
     
 0.488
Nham_0057
DNA helicase/exodeoxyribonuclease V, subunit B.
     
 0.423
Your Current Organism:
Nitrobacter hamburgensis
NCBI taxonomy Id: 323097
Other names: N. hamburgensis X14, Nitrobacter hamburgensis X14, Nitrobacter hamburgensis str. X14, Nitrobacter hamburgensis strain X14
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