node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nham_0102 | Nham_1762 | Nham_0102 | Nham_1762 | Chromosome segregation DNA-binding protein; Belongs to the ParB family. | Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.421 |
Nham_0102 | polA | Nham_0102 | Nham_0453 | Chromosome segregation DNA-binding protein; Belongs to the ParB family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.429 |
Nham_0102 | smc | Nham_0102 | Nham_3230 | Chromosome segregation DNA-binding protein; Belongs to the ParB family. | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.455 |
Nham_0102 | topA | Nham_0102 | Nham_2437 | Chromosome segregation DNA-binding protein; Belongs to the ParB family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.437 |
Nham_0780 | smc | Nham_0780 | Nham_3230 | Histone deacetylase superfamily. | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.517 |
Nham_1761 | Nham_1762 | Nham_1761 | Nham_1762 | Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.999 |
Nham_1761 | smc | Nham_1761 | Nham_3230 | Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.957 |
Nham_1762 | Nham_0102 | Nham_1762 | Nham_0102 | Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Chromosome segregation DNA-binding protein; Belongs to the ParB family. | 0.421 |
Nham_1762 | Nham_1761 | Nham_1762 | Nham_1761 | Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.999 |
Nham_1762 | smc | Nham_1762 | Nham_3230 | Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.851 |
Nham_3229 | polA | Nham_3229 | Nham_0453 | Twin-arginine translocation pathway signal. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.503 |
Nham_3229 | smc | Nham_3229 | Nham_3230 | Twin-arginine translocation pathway signal. | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.479 |
Nham_3231 | smc | Nham_3231 | Nham_3230 | Methyltransferase type 12. | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.506 |
gyrB | polA | Nham_0004 | Nham_0453 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.659 |
gyrB | smc | Nham_0004 | Nham_3230 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.457 |
gyrB | topA | Nham_0004 | Nham_2437 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.581 |
parE | polA | Nham_2317 | Nham_0453 | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.659 |
parE | smc | Nham_2317 | Nham_3230 | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.457 |
parE | topA | Nham_2317 | Nham_2437 | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.640 |
polA | Nham_0102 | Nham_0453 | Nham_0102 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Chromosome segregation DNA-binding protein; Belongs to the ParB family. | 0.429 |