STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nham_3563Sulfate adenylyltransferase subunit 2. (268 aa)    
Predicted Functional Partners:
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 0.999
Nham_3558
Sulfate ABC transporter, permease protein CysW.
 
 
 0.995
cysA
Sulphate transport system permease protein 1; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
 
 
 0.994
Nham_3560
Thiosulphate-binding protein.
 
 
 0.994
Nham_3559
Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 
 0.993
Nham_3561
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite.
 
 
 0.989
Nham_3562
uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.981
cysQ
3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
 
 
 0.949
Nham_0682
Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
 
  
 0.940
cysI
Sulfite reductase (NADPH) beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.936
Your Current Organism:
Nitrobacter hamburgensis
NCBI taxonomy Id: 323097
Other names: N. hamburgensis X14, Nitrobacter hamburgensis X14, Nitrobacter hamburgensis str. X14, Nitrobacter hamburgensis strain X14
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.