Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Nwi_2425L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (509 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.999
Nwi_2426
Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family.
  
 0.999
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.913
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.911
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
  0.901
Nwi_2423
Conserved hypothetical protein.
 
     0.840
Nwi_1845
Citrate synthase; Belongs to the citrate synthase family.
     
 0.829
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.828
Nwi_2980
Aminotransferase.
   
 
 0.814
Nwi_1294
Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family.
     
 0.813
Your Current Organism:
Nitrobacter winogradskyi
NCBI taxonomy Id: 323098
Other names: N. winogradskyi Nb-255, Nitrobacter winogradskyi Nb-255, Nitrobacter winogradskyi str. Nb-255, Nitrobacter winogradskyi strain Nb-255
Server load: low (24%) [HD]