STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mhun_0540Dihydroorotase, multifunctional complex type. (431 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase.
 0.999
carB
Carbamoyl-phosphate synthase large subunit.
 
 0.998
carA
Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family.
  
 0.997
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.997
Mhun_1153
Dihydroorotate oxidase B, electron transfer subunit.
 
 
 0.989
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.975
Mhun_2545
Orotidine-5'-phosphate decarboxylase.
  
  
 0.965
Mhun_1416
Uracil-xanthine permease.
  
  
 0.960
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
 
  
 0.951
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.930
Your Current Organism:
Methanospirillum hungatei
NCBI taxonomy Id: 323259
Other names: M. hungatei JF-1, Methanospirillum hungatei DSM 864, Methanospirillum hungatei JF-1, Methanospirillum hungatei NBRC 100397, Methanospirillum hungatei str. JF-1, Methanospirillum hungatei strain JF-1
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.