node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mhun_0630 | Mhun_1241 | Mhun_0630 | Mhun_1241 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit. | 0.998 |
Mhun_0630 | Mhun_1242 | Mhun_0630 | Mhun_1242 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Acetolactate synthase, large subunit. | 0.828 |
Mhun_0630 | Mhun_1797 | Mhun_0630 | Mhun_1797 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase. | 0.763 |
Mhun_0630 | Mhun_1799 | Mhun_0630 | Mhun_1799 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, small subunit. | 0.734 |
Mhun_0630 | cimA | Mhun_0630 | Mhun_1243 | Pyruvate oxidase; Belongs to the TPP enzyme family. | (R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.937 |
Mhun_0630 | ilvC | Mhun_0630 | Mhun_1245 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.877 |
Mhun_0630 | ilvE | Mhun_0630 | Mhun_0672 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.932 |
Mhun_0630 | leuC | Mhun_0630 | Mhun_1800 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.697 |
Mhun_0630 | leuC-2 | Mhun_0630 | Mhun_2361 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.936 |
Mhun_0630 | leuD | Mhun_0630 | Mhun_2362 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.944 |
Mhun_1241 | Mhun_0630 | Mhun_1241 | Mhun_0630 | Acetolactate synthase, small subunit. | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.998 |
Mhun_1241 | Mhun_1242 | Mhun_1241 | Mhun_1242 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit. | 0.999 |
Mhun_1241 | Mhun_1797 | Mhun_1241 | Mhun_1797 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase. | 0.876 |
Mhun_1241 | Mhun_1799 | Mhun_1241 | Mhun_1799 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, small subunit. | 0.868 |
Mhun_1241 | cimA | Mhun_1241 | Mhun_1243 | Acetolactate synthase, small subunit. | (R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.997 |
Mhun_1241 | ilvC | Mhun_1241 | Mhun_1245 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
Mhun_1241 | ilvE | Mhun_1241 | Mhun_0672 | Acetolactate synthase, small subunit. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.855 |
Mhun_1241 | leuC | Mhun_1241 | Mhun_1800 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.840 |
Mhun_1241 | leuC-2 | Mhun_1241 | Mhun_2361 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.840 |
Mhun_1241 | leuD | Mhun_1241 | Mhun_2362 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.837 |