STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mhun_2984Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake. (216 aa)    
Predicted Functional Partners:
Mhun_2982
Phosphate ABC transporter membrane protein 2, PhoT family; TC 3.A.1.7.1.
 
  
 0.991
pstB
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.991
Mhun_2985
Phosphate ABC transporter substrate-binding protein, PhoT family; TC 3.A.1.7.1.
 
  
 0.895
Mhun_1652
Phosphate ABC transporter substrate-binding protein, PhoT family; TC 3.A.1.7.1.
 
  
 0.878
Mhun_2411
Peptidase S26B, signal peptidase.
  
  
 0.666
Mhun_0605
Conserved hypothetical protein.
  
    0.661
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.575
Mhun_2988
Metallophosphoesterase.
       0.554
Mhun_0897
Phosphate uptake regulator, PhoU.
 
   
 0.540
Mhun_0977
Peptidase U62, modulator of DNA gyrase.
  
  
 0.475
Your Current Organism:
Methanospirillum hungatei
NCBI taxonomy Id: 323259
Other names: M. hungatei JF-1, Methanospirillum hungatei DSM 864, Methanospirillum hungatei JF-1, Methanospirillum hungatei NBRC 100397, Methanospirillum hungatei str. JF-1, Methanospirillum hungatei strain JF-1
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