STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noc_1316Thiamine pyrophosphate enzyme. (384 aa)    
Predicted Functional Partners:
Noc_1317
2,3-dimethylmalate lyase.
 0.998
phnW
Aminotransferase, class V; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
 
 
 0.996
Noc_2519
Acetolactate synthase, small subunit.
  
 
 0.967
Noc_1318
Conserved hypothetical protein.
 
     0.942
Noc_1582
Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase.
  
  
 0.911
Noc_0649
DNA topoisomerase I.
  
    0.852
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.844
Noc_0213
CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.802
Noc_0244
Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+).
  
  
 0.790
Noc_1748
Conserved hypothetical protein 374.
 
    0.787
Your Current Organism:
Nitrosococcus oceani
NCBI taxonomy Id: 323261
Other names: N. oceani ATCC 19707, Nitrosococcus oceani ATCC 19707, Nitrosococcus oceani C-107, Nitrosococcus oceani NCIMB 11848, Nitrosococcus oceani str. ATCC 19707, Nitrosococcus oceani strain ATCC 19707
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