Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noc_2148Heat shock protein DnaJ-like protein. (252 aa)    
Predicted Functional Partners:
Noc_2149
Conserved hypothetical protein.
 
     0.956
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.945
Noc_0623
Plasmid segregation actin-type ATPase ParM.
  
 0.923
Noc_0667
Heat shock protein Hsp70.
  
 0.923
dnaK
Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.923
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.922
groL
Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.875
Noc_0962
Histone deacetylase superfamily.
    
  0.748
Noc_1032
Hypothetical protein.
  
 0.745
prmA
[LSU ribosomal protein L11P]-lysine N-methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
  
  
 0.745
Your Current Organism:
Nitrosococcus oceani
NCBI taxonomy Id: 323261
Other names: N. oceani ATCC 19707, Nitrosococcus oceani ATCC 19707, Nitrosococcus oceani C-107, Nitrosococcus oceani NCIMB 11848, Nitrosococcus oceani str. ATCC 19707, Nitrosococcus oceani strain ATCC 19707
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