node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABB73315.1 | anmK | Nmul_A0006 | Nmul_A0555 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.529 |
ABB73315.1 | murA | Nmul_A0006 | Nmul_A0886 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.542 |
ABB73315.1 | murB | Nmul_A0006 | Nmul_A2492 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.479 |
ABB73531.1 | ABB75109.1 | Nmul_A0223 | Nmul_A1812 | Major facilitator superfamily MFS_1. | Negative regulator of AmpC, AmpD. | 0.583 |
ABB73531.1 | anmK | Nmul_A0223 | Nmul_A0555 | Major facilitator superfamily MFS_1. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.579 |
ABB73531.1 | nagZ | Nmul_A0223 | Nmul_A1761 | Major facilitator superfamily MFS_1. | Beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.614 |
ABB73862.1 | ABB74277.1 | Nmul_A0554 | Nmul_A0974 | Peptidase M23B. | Glycosyl transferase, family 51. | 0.434 |
ABB73862.1 | anmK | Nmul_A0554 | Nmul_A0555 | Peptidase M23B. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.782 |
ABB74277.1 | ABB73862.1 | Nmul_A0974 | Nmul_A0554 | Glycosyl transferase, family 51. | Peptidase M23B. | 0.434 |
ABB74277.1 | ABB75109.1 | Nmul_A0974 | Nmul_A1812 | Glycosyl transferase, family 51. | Negative regulator of AmpC, AmpD. | 0.459 |
ABB74277.1 | anmK | Nmul_A0974 | Nmul_A0555 | Glycosyl transferase, family 51. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.410 |
ABB74277.1 | murA | Nmul_A0974 | Nmul_A0886 | Glycosyl transferase, family 51. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.491 |
ABB74277.1 | murB | Nmul_A0974 | Nmul_A2492 | Glycosyl transferase, family 51. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.553 |
ABB74277.1 | nagZ | Nmul_A0974 | Nmul_A1761 | Glycosyl transferase, family 51. | Beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.437 |
ABB75109.1 | ABB73531.1 | Nmul_A1812 | Nmul_A0223 | Negative regulator of AmpC, AmpD. | Major facilitator superfamily MFS_1. | 0.583 |
ABB75109.1 | ABB74277.1 | Nmul_A1812 | Nmul_A0974 | Negative regulator of AmpC, AmpD. | Glycosyl transferase, family 51. | 0.459 |
ABB75109.1 | anmK | Nmul_A1812 | Nmul_A0555 | Negative regulator of AmpC, AmpD. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.626 |
ABB75109.1 | nagZ | Nmul_A1812 | Nmul_A1761 | Negative regulator of AmpC, AmpD. | Beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.545 |
anmK | ABB73315.1 | Nmul_A0555 | Nmul_A0006 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.529 |
anmK | ABB73531.1 | Nmul_A0555 | Nmul_A0223 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Major facilitator superfamily MFS_1. | 0.579 |