STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABB75522.1Hydroxypyruvate reductase. (451 aa)    
Predicted Functional Partners:
ABB75143.1
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein.
 
 0.952
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.936
gpmA1
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
     
  0.900
gpmA2
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
     
  0.900
ABB74810.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.847
ABB73693.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.825
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.825
ABB74301.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
  0.811
ABB73695.1
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
  0.801
ABB73666.1
2-oxo-acid dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
  0.800
Your Current Organism:
Nitrosospira multiformis
NCBI taxonomy Id: 323848
Other names: N. multiformis ATCC 25196, Nitrosospira multiformis ATCC 25196, Nitrosospira multiformis C-71, Nitrosospira multiformis NCIMB 11849, Nitrosospira multiformis NI13, Nitrosospira multiformis str. ATCC 25196, Nitrosospira multiformis strain ATCC 25196
Server load: low (12%) [HD]