node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABB73871.1 | ABB75710.1 | Nmul_A0563 | Nmul_A2421 | ATP-dependent DNA helicase UvrD. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.585 |
ABB73871.1 | mfd | Nmul_A0563 | Nmul_A0639 | ATP-dependent DNA helicase UvrD. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.477 |
ABB73871.1 | polA | Nmul_A0563 | Nmul_A0568 | ATP-dependent DNA helicase UvrD. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.845 |
ABB73871.1 | recA | Nmul_A0563 | Nmul_A0019 | ATP-dependent DNA helicase UvrD. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.935 |
ABB73871.1 | uvrA | Nmul_A0563 | Nmul_A2229 | ATP-dependent DNA helicase UvrD. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.698 |
ABB75710.1 | ABB73871.1 | Nmul_A2421 | Nmul_A0563 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | ATP-dependent DNA helicase UvrD. | 0.585 |
ABB75710.1 | ABB75883.1 | Nmul_A2421 | Nmul_A2596 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Putative prophage repressor; Belongs to the peptidase S24 family. | 0.845 |
ABB75710.1 | hrcA | Nmul_A2421 | Nmul_A2423 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.663 |
ABB75710.1 | mfd | Nmul_A2421 | Nmul_A0639 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.637 |
ABB75710.1 | nadK | Nmul_A2421 | Nmul_A2422 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.968 |
ABB75710.1 | polA | Nmul_A2421 | Nmul_A0568 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.566 |
ABB75710.1 | recA | Nmul_A2421 | Nmul_A0019 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.865 |
ABB75710.1 | ruvA | Nmul_A2421 | Nmul_A2720 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.557 |
ABB75710.1 | uvrA | Nmul_A2421 | Nmul_A2229 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.561 |
ABB75710.1 | xseA | Nmul_A2421 | Nmul_A1030 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.600 |
ABB75883.1 | ABB75710.1 | Nmul_A2596 | Nmul_A2421 | Putative prophage repressor; Belongs to the peptidase S24 family. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.845 |
ABB75883.1 | polA | Nmul_A2596 | Nmul_A0568 | Putative prophage repressor; Belongs to the peptidase S24 family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.520 |
ABB75883.1 | recA | Nmul_A2596 | Nmul_A0019 | Putative prophage repressor; Belongs to the peptidase S24 family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.991 |
hrcA | ABB75710.1 | Nmul_A2423 | Nmul_A2421 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.663 |
hrcA | nadK | Nmul_A2423 | Nmul_A2422 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.542 |