Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Shew_0280Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_0316 transcriptional regulator, GntR family. (233 aa)    
Predicted Functional Partners:
Shew_3432
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_3600 regulatory protein GntR, HTH.
 
  
 0.718
Shew_3176
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sfr:Sfri_3695 regulatory protein GntR, HTH.
 
  
 0.708
Shew_1775
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sdn:Sden_2123 acetolactate synthase, small subunit.
  
    0.577
prpB
2,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.570
Shew_1823
Methylitaconate delta2-delta3-isomerase; TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: pen:PSEEN1906 hypothetical protein.
 
  
 0.479
Shew_0281
PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_3626 phospholipid/glycerol acyltransferase.
       0.448
Shew_0279
Hypothetical protein.
       0.441
Shew_0282
PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_0319 phospholipid/glycerol acyltransferase.
       0.413
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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