Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Shew_1002Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (117 aa)    
Predicted Functional Partners:
Shew_1003
TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
  
 
 0.995
Shew_2833
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.993
Shew_3132
KEGG: shm:Shewmr7_3295 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
 
 
 0.988
folE
PFAM: GTP cyclohydrolase I; KEGG: son:SO4254 GTP cyclohydrolase I.
 
  
 0.933
Shew_0832
PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0641 twin-arginine translocation pathway signal.
     
 0.904
Shew_0048
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdn:Sden_0827 short-chain dehydrogenase/reductase SDR.
    
  0.901
Shew_1157
PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0584 alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
 0.900
Shew_1158
PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0583 alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
 0.900
Shew_3226
PFAM: Alkaline phosphatase; KEGG: she:Shewmr4_0688 alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
 0.900
Shew_2305
TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: sfr:Sfri_1396 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.
  
  
 0.748
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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