Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Shew_1920PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_1942 alpha/beta hydrolase fold. (255 aa)    
Predicted Functional Partners:
Shew_1919
KEGG: shm:Shewmr7_1941 hypothetical protein.
       0.670
Shew_1505
KEGG: shm:Shewmr7_2484 hypothetical protein.
      0.590
Shew_1917
Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
       0.589
Shew_1918
PFAM: CopG domain protein DNA-binding domain protein; KEGG: sdn:Sden_1989 CopG-like DNA-binding.
       0.574
seqA
SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
       0.565
Shew_1922
TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sfr:Sfri_1915 phosphoglucomutase, alpha-D-glucose phosphate-specific.
   
   0.541
Shew_1108
KEGG: she:Shewmr4_2947 methylation site containing protein.
   
    0.521
apaH
Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
  0.453
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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