STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Shew_1968PFAM: beta-lactamase; KEGG: cps:CPS_1414 putative beta-lactamase. (380 aa)    
Predicted Functional Partners:
Shew_3220
Beta-lactamase; PFAM: penicillin-binding protein, transpeptidase; KEGG: shm:Shewmr7_3328 beta-lactamase.
      
 0.630
Shew_2892
PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_0812 major facilitator superfamily MFS_1.
      
 0.621
Shew_3434
PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: sfr:Sfri_3780 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD.
      
 0.612
Shew_1967
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sfr:Sfri_2093 amidohydrolase.
 
     0.543
Shew_2964
PFAM: beta-lactamase; KEGG: shm:Shewmr7_3266 beta-lactamase.
  
   
0.529
nagZ
Glycoside hydrolase, family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
  
  
 0.485
Shew_1114
PFAM: SapC family protein; KEGG: pha:PSHAa1142 hypothetical protein.
  
     0.434
Shew_1969
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: son:SO1416 DNA-binding response regulator.
       0.425
Shew_1970
Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO1417 sensor histidine kinase.
       0.425
Shew_0257
PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: sdn:Sden_0280 peptidase S9, prolyl oligopeptidase active site region.
 
     0.415
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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