Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Shew_1982PFAM: phage integrase family protein; KEGG: shm:Shewmr7_1973 phage integrase family protein; Belongs to the 'phage' integrase family. (423 aa)    
Predicted Functional Partners:
Shew_3002
KEGG: she:Shewmr4_2079 hypothetical protein.
  
    0.605
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.516
Shew_1068
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: sfr:Sfri_2915 chorismate mutase.
  
    0.514
Shew_3039
PFAM: protein of unknown function DUF159; KEGG: sdn:Sden_3234 protein of unknown function DUF159; Belongs to the SOS response-associated peptidase family.
   
    0.503
Shew_3629
KEGG: she:Shewmr4_3805 competence protein ComF.
   
    0.501
Shew_0988
Hypothetical protein; KEGG: rme:Rmet_2827 putative TraY/DotA-like type IV secretion system protein.
  
     0.466
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
 
   
 0.445
rpsJ
SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
    
 
 0.417
rpsU
PFAM: ribosomal protein S21; KEGG: shm:Shewmr7_2987 ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
   
 
 0.403
Shew_0810
PFAM: pentapeptide repeat protein; Ion transport 2 domain protein,; KEGG: vvy:VV0782 putative potassium channel protein.
  
     0.402
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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