Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Shew_2162TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: shm:Shewmr7_1591 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family. (694 aa)    
Predicted Functional Partners:
Shew_1285
5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_1223 metallophosphoesterase; Belongs to the 5'-nucleotidase family.
 
 
 0.976
rihA
Purine nucleosidase; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
 
 
  0.947
Shew_0363
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yps:YPTB2218 haloacid dehalogenase-like hydrolase family protein.
   
 
 0.928
Shew_2135
5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sfr:Sfri_2309 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
  
 
0.927
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
 
  
  0.922
deoD
TIGRFAM: purine nucleoside phosphorylase; PFAM: purine and other phosphorylases, family 1; KEGG: shm:Shewmr7_1105 purine nucleoside phosphorylase.
    
 0.914
Shew_1511
TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: she:Shewmr4_2382 HAD-superfamily hydrolase, subfamily IIA.
  
 
 0.913
surE
5'-nucleotidase / 3'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.906
udk
TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: shm:Shewmr7_1732 uridine kinase.
  
 
  0.904
add
KEGG: son:SO4731 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
    
 0.904
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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