Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Shew_2170Endonuclease/exonuclease/phosphatase; PFAM: PKD domain containing protein; Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_1534 PKD domain containing protein. (945 aa)    
Predicted Functional Partners:
Shew_1779
KEGG: she:Shewmr4_1752 alkaline phosphatase.
   
 0.864
Shew_2135
5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sfr:Sfri_2309 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
   
 0.585
Shew_0781
PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: sfr:Sfri_0513 peptidase S8 and S53, subtilisin, kexin, sedolisin; Belongs to the peptidase S8 family.
  
    0.541
Shew_3021
PFAM: peptidase domain protein; Endonuclease I; KEGG: sdn:Sden_3289 endonuclease I.
   
 0.483
Shew_2162
TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: shm:Shewmr7_1591 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family.
 
   
 0.477
Shew_2351
KEGG: shm:Shewmr7_1652 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region.
  
   
 0.477
Shew_3223
PFAM: Endonuclease I; KEGG: she:Shewmr4_0691 deoxyribonuclease I.
     
 0.471
Shew_0832
PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0641 twin-arginine translocation pathway signal.
 
  
 0.447
Shew_2169
Hypothetical protein; KEGG: pat:Patl_2065 UspA.
       0.410
Shew_3670
PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_3954 metal dependent phosphohydrolase.
      
 0.409
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
Server load: medium (46%) [HD]