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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Shew_3000TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cps:CPS_0546 GGDEF domain protein. (585 aa)    
Predicted Functional Partners:
Shew_0951
PFAM: EAL domain protein; response regulator receiver; KEGG: pha:PSHAa0134 hypothetical protein.
 
   0.818
Shew_2781
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_1066 diguanylate cyclase/phosphodiesterase.
  
   0.805
Shew_0919
Diguanylate phosphodiesterase; PFAM: EAL domain protein; phosphotransferase system, EIIC; KEGG: shm:Shewmr7_3254 diguanylate phosphodiesterase.
  
    0.793
Shew_2065
Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_2063 diguanylate cyclase/phosphodiesterase.
  
    0.781
Shew_0384
Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_0461 diguanylate cyclase/phosphodiesterase.
  
    0.754
Shew_2998
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sdn:Sden_0949 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase.
 
     0.750
Shew_2999
KEGG: cps:CPS_0547 hypothetical protein.
       0.714
Shew_0436
Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_3475 diguanylate cyclase/phosphodiesterase.
 
    0.691
Shew_1882
PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sfr:Sfri_2300 metal dependent phosphohydrolase.
  
    0.596
Shew_2997
KEGG: cps:CPS_0544 hypothetical protein.
 
     0.514
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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