Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smgPFAM: protein of unknown function DUF494; KEGG: sfr:Sfri_0027 protein of unknown function DUF494; Belongs to the Smg family. (157 aa)    
Predicted Functional Partners:
Shew_3734
TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: son:SO0034 DNA processing protein DprA, putative.
     
 0.832
Shew_3735
PFAM: Peptidoglycan-binding LysM; KEGG: son:SO0033 LysM domain protein.
 
     0.725
zapD
Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
  
     0.717
Shew_2928
PFAM: protein of unknown function DUF1451; KEGG: shm:Shewmr7_1063 protein of unknown function DUF1451.
  
     0.644
Shew_0304
PFAM: protein of unknown function DUF526; KEGG: shm:Shewmr7_3651 protein of unknown function DUF526.
  
     0.593
ftsL
Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.587
def-2
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
  
    0.556
Shew_1939
PFAM: protein of unknown function DUF1315; KEGG: son:SO2422 hypothetical protein.
  
     0.554
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.549
Shew_3738
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
       0.549
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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