STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_0075PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: rrs:RoseRS_0743 D12 class N6 adenine-specific DNA methyltransferase. (299 aa)    
Predicted Functional Partners:
Caur_1151
KEGG: rca:Rcas_0884 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
  
  
  0.959
Caur_3352
KEGG: rca:Rcas_2236 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
  
  
  0.947
Caur_0076
KEGG: rrs:RoseRS_0742 hypothetical protein.
    
 0.935
Caur_0721
PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: drm:Dred_0878 D12 class N6 adenine-specific DNA methyltransferase.
  
  
  0.925
Caur_2526
PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: swo:Swol_0503 site-specific DNA methylase-like protein.
  
  
  0.925
Caur_0658
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rca:Rcas_3693 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family.
 
  
 0.531
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
      
 0.491
Caur_0074
PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; KEGG: gvi:gll3709 polysaccharide transporter, PST family.
       0.477
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
      
 0.474
hisA
TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: rca:Rcas_2920 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
      
 0.472
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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