Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_0109PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rca:Rcas_1176 two component transcriptional regulator, winged helix family. (228 aa)    
Predicted Functional Partners:
Caur_0110
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rrs:RoseRS_0804 integral membrane sensor signal transduction histidine kinase.
   0.945
Caur_2069
PFAM: response regulator receiver; KEGG: reh:H16_B2354 signal transduction histidine kinase containing two receiver domains (hybrid).
 
 
 0.928
Caur_2824
Histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rca:Rcas_0155 multi-sensor signal transduction histidine kinase.
 
 
 0.913
Caur_3274
PAS sensor protein; KEGG: sfu:Sfum_0942 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-4 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein.
  
 
 0.878
Caur_3108
PAS sensor protein; KEGG: dar:Daro_3006 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.844
Caur_1776
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: dsy:DSY0353 hypothetical protein.
 
   0.837
Caur_3392
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rca:Rcas_0352 integral membrane sensor signal transduction histidine kinase.
   0.834
Caur_3527
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rca:Rcas_0230 integral membrane sensor signal transduction histidine kinase.
 
   0.827
Caur_0238
KEGG: sfu:Sfum_1007 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.821
Caur_2130
KEGG: nha:Nham_0235 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; GAF domain protein.
  
 
 0.821
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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