Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pheAPFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: rrs:RoseRS_1964 prephenate dehydratase. (284 aa)    
Predicted Functional Partners:
Caur_2355
PFAM: aminotransferase class I and II; KEGG: drm:Dred_1696 aminotransferase, class I and II.
 
 
 0.990
Caur_2517
PFAM: oxidoreductase domain protein; Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: rrs:RoseRS_2023 prephenate dehydrogenase.
 
 0.970
Caur_2228
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase of the AroH class; KEGG: rrs:RoseRS_2360 chorismate mutase.
    
 0.929
Caur_0698
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase.
 
  
 0.925
hisC
KEGG: mta:Moth_0515 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class V; aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.923
hisC-2
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: rca:Rcas_0200 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.923
Caur_2229
KEGG: rca:Rcas_3120 phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA.
 
  
 0.923
Caur_2799
PFAM: aromatic amino acid hydroxylase; KEGG: sru:SRU_2069 tryptophan 5-hydroxylase 1.
     
 0.914
Caur_1911
PFAM: aminotransferase class I and II; KEGG: rca:Rcas_3728 aminotransferase class I and II.
 
  
 0.907
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
  
 0.809
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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