node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Caur_0176 | Caur_0177 | Caur_0176 | Caur_0177 | Hypothetical protein. | Hypothetical protein. | 0.773 |
Caur_0176 | mclA | Caur_0176 | Caur_0174 | Hypothetical protein. | HpcH/HpaI aldolase; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation, and in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. As a part of the 3-hydroxypropionate cycle, it catalyzes the cleavage of (S)-malyl-CoA to yield acetyl-CoA and glyoxylate. As part of the glyoxylate assimilation cycle, it catalyzes the condensation of glyoxylate with propionyl-CoA to yield (2R,3S)- beta-methylmalyl-CoA, and catalyzes the cleavage of (S)-citramalyl-CoA to yield acetyl-CoA and pyruva [...] | 0.419 |
Caur_0176 | mct | Caur_0176 | Caur_0175 | Hypothetical protein. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. This reaction involves an intramolecular CoA transferase that catalyzes the reversible transfer of the CoA moiety from the C1- carboxyl group of mesaconyl-CoA to the C4-carboxyl group. It does not require free mesaconate as CoA acceptor; Belongs to the CoA-transferase III family. Mesaconyl-CoA isomerase subfamily. | 0.512 |
Caur_0176 | smtA | Caur_0176 | Caur_0179 | Hypothetical protein. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity). | 0.418 |
Caur_0176 | smtB | Caur_0176 | Caur_0178 | Hypothetical protein. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity). | 0.773 |
Caur_0177 | Caur_0176 | Caur_0177 | Caur_0176 | Hypothetical protein. | Hypothetical protein. | 0.773 |
Caur_0177 | mclA | Caur_0177 | Caur_0174 | Hypothetical protein. | HpcH/HpaI aldolase; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation, and in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. As a part of the 3-hydroxypropionate cycle, it catalyzes the cleavage of (S)-malyl-CoA to yield acetyl-CoA and glyoxylate. As part of the glyoxylate assimilation cycle, it catalyzes the condensation of glyoxylate with propionyl-CoA to yield (2R,3S)- beta-methylmalyl-CoA, and catalyzes the cleavage of (S)-citramalyl-CoA to yield acetyl-CoA and pyruva [...] | 0.419 |
Caur_0177 | mct | Caur_0177 | Caur_0175 | Hypothetical protein. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. This reaction involves an intramolecular CoA transferase that catalyzes the reversible transfer of the CoA moiety from the C1- carboxyl group of mesaconyl-CoA to the C4-carboxyl group. It does not require free mesaconate as CoA acceptor; Belongs to the CoA-transferase III family. Mesaconyl-CoA isomerase subfamily. | 0.512 |
Caur_0177 | smtA | Caur_0177 | Caur_0179 | Hypothetical protein. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity). | 0.418 |
Caur_0177 | smtB | Caur_0177 | Caur_0178 | Hypothetical protein. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity). | 0.773 |
Caur_0583 | ldh | Caur_0583 | Caur_1675 | PFAM: Aldehyde Dehydrogenase_; KEGG: rrs:RoseRS_3204 aldehyde dehydrogenase. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.548 |
Caur_0583 | mch | Caur_0583 | Caur_0173 | PFAM: Aldehyde Dehydrogenase_; KEGG: rrs:RoseRS_3204 aldehyde dehydrogenase. | MaoC domain protein dehydratase; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. Catalyzes the reversible dehydration of beta-methylmalyl- CoA ((2R,3S)-beta-methylmalyl-CoA) to yield mesaconyl-CoA (methylfumaryl-CoA). | 0.543 |
Caur_0583 | mct | Caur_0583 | Caur_0175 | PFAM: Aldehyde Dehydrogenase_; KEGG: rrs:RoseRS_3204 aldehyde dehydrogenase. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. This reaction involves an intramolecular CoA transferase that catalyzes the reversible transfer of the CoA moiety from the C1- carboxyl group of mesaconyl-CoA to the C4-carboxyl group. It does not require free mesaconate as CoA acceptor; Belongs to the CoA-transferase III family. Mesaconyl-CoA isomerase subfamily. | 0.457 |
hisD | mct | Caur_2694 | Caur_0175 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. This reaction involves an intramolecular CoA transferase that catalyzes the reversible transfer of the CoA moiety from the C1- carboxyl group of mesaconyl-CoA to the C4-carboxyl group. It does not require free mesaconate as CoA acceptor; Belongs to the CoA-transferase III family. Mesaconyl-CoA isomerase subfamily. | 0.472 |
hisD | meh | Caur_2694 | Caur_0180 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Conserved hypothetical protein; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. Catalyzes the hydration of 3-methylfumaryl-CoA (mesaconyl-C4-CoA) to (3S)-citramalyl-CoA. | 0.440 |
ldh | Caur_0583 | Caur_1675 | Caur_0583 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | PFAM: Aldehyde Dehydrogenase_; KEGG: rrs:RoseRS_3204 aldehyde dehydrogenase. | 0.548 |
ldh | mct | Caur_1675 | Caur_0175 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. This reaction involves an intramolecular CoA transferase that catalyzes the reversible transfer of the CoA moiety from the C1- carboxyl group of mesaconyl-CoA to the C4-carboxyl group. It does not require free mesaconate as CoA acceptor; Belongs to the CoA-transferase III family. Mesaconyl-CoA isomerase subfamily. | 0.458 |
mch | Caur_0583 | Caur_0173 | Caur_0583 | MaoC domain protein dehydratase; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. Catalyzes the reversible dehydration of beta-methylmalyl- CoA ((2R,3S)-beta-methylmalyl-CoA) to yield mesaconyl-CoA (methylfumaryl-CoA). | PFAM: Aldehyde Dehydrogenase_; KEGG: rrs:RoseRS_3204 aldehyde dehydrogenase. | 0.543 |
mch | mclA | Caur_0173 | Caur_0174 | MaoC domain protein dehydratase; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. Catalyzes the reversible dehydration of beta-methylmalyl- CoA ((2R,3S)-beta-methylmalyl-CoA) to yield mesaconyl-CoA (methylfumaryl-CoA). | HpcH/HpaI aldolase; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation, and in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. As a part of the 3-hydroxypropionate cycle, it catalyzes the cleavage of (S)-malyl-CoA to yield acetyl-CoA and glyoxylate. As part of the glyoxylate assimilation cycle, it catalyzes the condensation of glyoxylate with propionyl-CoA to yield (2R,3S)- beta-methylmalyl-CoA, and catalyzes the cleavage of (S)-citramalyl-CoA to yield acetyl-CoA and pyruva [...] | 0.997 |
mch | mct | Caur_0173 | Caur_0175 | MaoC domain protein dehydratase; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. Catalyzes the reversible dehydration of beta-methylmalyl- CoA ((2R,3S)-beta-methylmalyl-CoA) to yield mesaconyl-CoA (methylfumaryl-CoA). | L-carnitine dehydratase/bile acid-inducible protein F; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. This reaction involves an intramolecular CoA transferase that catalyzes the reversible transfer of the CoA moiety from the C1- carboxyl group of mesaconyl-CoA to the C4-carboxyl group. It does not require free mesaconate as CoA acceptor; Belongs to the CoA-transferase III family. Mesaconyl-CoA isomerase subfamily. | 0.962 |