STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_0235TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: rca:Rcas_0982 putative hydroxymethylglutaryl-CoA synthase. (349 aa)    
Predicted Functional Partners:
Caur_0232
PFAM: protein of unknown function DUF35; KEGG: rca:Rcas_0984 protein of unknown function DUF35.
 
 
 0.999
Caur_0234
KEGG: rca:Rcas_0983 acetyl-CoA acetyltransferase-like protein.
 
 0.999
Caur_0236
TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; KEGG: rca:Rcas_0981 hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
 
 
 0.998
Caur_1461
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: rca:Rcas_0702 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.996
Caur_1540
KEGG: rca:Rcas_3206 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.996
Caur_3220
KEGG: rrs:RoseRS_2969 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.996
Caur_3221
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rca:Rcas_1887 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
 0.935
Caur_3394
TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: rrs:RoseRS_1953 acetoacetyl-CoA synthase.
   
 
 0.928
Caur_1565
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rca:Rcas_0977 enoyl-CoA hydratase/isomerase.
  
 0.923
FabG
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.914
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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