Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_0342PFAM: histone deacetylase superfamily; KEGG: rrs:RoseRS_3190 histone deacetylase superfamily. (352 aa)    
Predicted Functional Partners:
Caur_2161
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: rca:Rcas_2830 AAA ATPase central domain protein.
   
 0.848
hisA
TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: rca:Rcas_2920 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
   
   0.827
Caur_2699
PFAM: SNF2-related protein; helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sat:SYN_00017 superfamily II DNA/RNA helicase, SNF2 family.
   
 0.825
Caur_0613
PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: rrs:RoseRS_3202 AMP-dependent synthetase and ligase.
 
 
 0.824
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.795
Caur_1376
PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: rrs:RoseRS_2925 amine oxidase.
   
 0.785
Caur_2249
PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: rrs:RoseRS_2925 amine oxidase.
   
 0.785
cobB
PFAM: Silent information regulator protein Sir2; KEGG: rxy:Rxyl_1341 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
    
 0.784
Caur_0345
KEGG: rca:Rcas_2921 hypothetical protein.
   
 0.781
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
    
 0.777
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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