| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Caur_3282 | fhs | Caur_3282 | Caur_2634 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.628 |
| Caur_3282 | purC | Caur_3282 | Caur_1261 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | PFAM: SAICAR synthetase; KEGG: rca:Rcas_1843 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | 0.990 |
| Caur_3282 | purD | Caur_3282 | Caur_0629 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | KEGG: rca:Rcas_3175 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.924 |
| Caur_3282 | purF | Caur_3282 | Caur_1601 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.997 |
| Caur_3282 | purH | Caur_3282 | Caur_2058 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | KEGG: rrs:RoseRS_0206 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.962 |
| Caur_3282 | purK | Caur_3282 | Caur_2314 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.916 |
| Caur_3282 | purL | Caur_3282 | Caur_3365 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.996 |
| Caur_3282 | purM | Caur_3282 | Caur_1262 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | KEGG: rrs:RoseRS_2554 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.997 |
| Caur_3282 | purN | Caur_3282 | Caur_0630 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
| Caur_3282 | purQ | Caur_3282 | Caur_0744 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.969 |
| fhs | Caur_3282 | Caur_2634 | Caur_3282 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rca:Rcas_0551 phosphoribosylamine--glycine ligase. | 0.628 |
| fhs | purC | Caur_2634 | Caur_1261 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | PFAM: SAICAR synthetase; KEGG: rca:Rcas_1843 phosphoribosylaminoimidazolesuccinocarboxamide synthase. | 0.876 |
| fhs | purD | Caur_2634 | Caur_0629 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | KEGG: rca:Rcas_3175 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.628 |
| fhs | purF | Caur_2634 | Caur_1601 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.840 |
| fhs | purH | Caur_2634 | Caur_2058 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | KEGG: rrs:RoseRS_0206 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.989 |
| fhs | purK | Caur_2634 | Caur_2314 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.489 |
| fhs | purL | Caur_2634 | Caur_3365 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.936 |
| fhs | purM | Caur_2634 | Caur_1262 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | KEGG: rrs:RoseRS_2554 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.500 |
| fhs | purN | Caur_2634 | Caur_0630 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.983 |
| fhs | purQ | Caur_2634 | Caur_0744 | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.459 |