Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (163 aa)    
Predicted Functional Partners:
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.999
Caur_1872
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: rrs:RoseRS_3195 molybdopterin converting factor, subunit 1.
 
 0.999
Caur_0396
Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
  
 0.996
Caur_2104
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
 0.941
Caur_3491
PFAM: thiamineS protein; KEGG: rrs:RoseRS_0722 thiamineS protein.
  
  
 0.930
Caur_1871
TIGRFAM: molybdopterin converting factor, subunit 1; MoaD family protein; PFAM: thiamineS protein; KEGG: rrs:RoseRS_3195 molybdopterin converting factor, subunit 1.
 
  
 0.893
Caur_2582
KEGG: sus:Acid_5295 hypothetical protein.
  
  
 0.815
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: rrs:RoseRS_1252 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
    
 0.785
Caur_2491
Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
   
 0.781
Caur_2528
PFAM: MOSC domain containing protein; KEGG: dge:Dgeo_0846 MOSC domain protein.
 
  
 0.730
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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