STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_0838PFAM: thioesterase superfamily protein; KEGG: ajs:Ajs_1073 uncharacterized domain 1. (164 aa)    
Predicted Functional Partners:
Caur_1085
PFAM: AMP-dependent synthetase and ligase; KEGG: rca:Rcas_0545 AMP-dependent synthetase and ligase.
 
   
 0.701
Caur_1080
KEGG: rca:Rcas_0540 coenzyme F390 synthetase-like protein.
 
  
 0.645
meh
Conserved hypothetical protein; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. Catalyzes the hydration of 3-methylfumaryl-CoA (mesaconyl-C4-CoA) to (3S)-citramalyl-CoA.
  
     0.618
Caur_1346
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rrs:RoseRS_4259 enoyl-CoA hydratase/isomerase.
 
 
 0.591
Caur_1690
Uncharacterized peroxidase-related enzyme; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
   
 0.528
Caur_3221
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rca:Rcas_1887 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
 
 0.526
Caur_1086
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rrs:RoseRS_0622 ABC transporter related.
 
     0.457
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
    0.443
Caur_2407
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: gtn:GTNG_1042 malonyl CoA-acyl carrier protein transacylase (FabD).
  
  
 0.424
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
  
 0.411
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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