Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Caur_0880TIGRFAM: mevalonate kinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: rrs:RoseRS_2135 mevalonate kinase. (311 aa)    
Predicted Functional Partners:
Caur_0236
TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; KEGG: rca:Rcas_0981 hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
 0.998
Caur_0617
PFAM: GHMP kinase domain protein; KEGG: rrs:RoseRS_4285 GHMP kinase, C terminal domain protein.
 
  
 0.973
pheT
KEGG: rrs:RoseRS_1038 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
  
 
 0.938
Caur_0235
TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: rca:Rcas_0982 putative hydroxymethylglutaryl-CoA synthase.
 
  
 0.818
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.813
Caur_0506
PFAM: aspartate/glutamate/uridylate kinase; KEGG: rca:Rcas_4059 aspartate/glutamate/uridylate kinase.
 
   
 0.716
Caur_0371
PFAM: pyruvate carboxyltransferase; KEGG: rrs:RoseRS_4162 pyruvate carboxyltransferase.
     
 0.625
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
  
 0.594
Caur_1877
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: nca:Noca_3292 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.
 
      0.482
Caur_0232
PFAM: protein of unknown function DUF35; KEGG: rca:Rcas_0984 protein of unknown function DUF35.
 
     0.478
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.