STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (309 aa)    
Predicted Functional Partners:
Caur_2080
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rca:Rcas_4052 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
  
 0.999
Caur_3809
KEGG: rrs:RoseRS_3488 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.993
Caur_1614
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic protein domain protein; malic protein NAD-binding; KEGG: rrs:RoseRS_2286 malate dehydrogenase (oxaloacetate-decarboxylating).
  
 0.939
Caur_2969
KEGG: cvi:CV_3304 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase; Belongs to the malate synthase family.
   
 0.929
Caur_2355
PFAM: aminotransferase class I and II; KEGG: drm:Dred_1696 aminotransferase, class I and II.
  
 0.920
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
    
 0.917
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
   
 
 0.913
Caur_3888
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
   
 
 0.913
Caur_1443
PFAM: fumarate lyase; KEGG: rrs:RoseRS_3341 fumarate lyase.
    
 0.908
Caur_1375
TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: rxy:Rxyl_2905 succinate-semialdehyde dehydrogenase (NAD(P)+); Belongs to the aldehyde dehydrogenase family.
   
 0.904
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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