Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Caur_0987TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: rca:Rcas_4076 phage SPO1 DNA polymerase-related protein. (210 aa)    
Predicted Functional Partners:
Caur_1990
PFAM: peptidase M22 glycoprotease; KEGG: rrs:RoseRS_4358 peptidase M22, glycoprotease.
  
    0.721
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.656
Caur_0988
KEGG: rrs:RoseRS_0874 hypothetical protein.
       0.616
Caur_1930
TIGRFAM: DNA polymerase III, delta prime subunit; SMART: AAA ATPase; KEGG: rrs:RoseRS_3588 DNA polymerase III, delta prime subunit.
 
  
 0.602
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
     
 0.561
dinG
DNA polymerase III, epsilon subunit; 3'-5' exonuclease.
 
   
 0.532
Caur_0986
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rca:Rcas_1939 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family.
       0.530
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
  
 0.527
Caur_2639
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
   
 0.517
Caur_0985
PFAM: glycosyl transferase family 2; KEGG: sru:SRU_1194 glycosyl transferase-related protein.
       0.496
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.