Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Caur_0992PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rrs:RoseRS_2126 glyoxalase/bleomycin resistance protein/dioxygenase. (126 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
       0.789
Caur_1567
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: rca:Rcas_3425 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
    0.579
Caur_1983
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: rrs:RoseRS_2993 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
    0.579
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
    0.579
Caur_3170
PFAM: nitroreductase; KEGG: mca:MCA1372 nitroreductase family protein; Belongs to the flavin oxidoreductase frp family.
 
  
 0.553
Caur_0994
PFAM: amine oxidase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: rrs:RoseRS_0137 amine oxidase.
       0.549
Caur_1624
KEGG: rrs:RoseRS_0413 ABC-type dipeptide transport system periplasmic component-like protein.
 
     0.548
nuoD1
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
    0.497
nuoD2
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
    0.497
Caur_0613
PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: rrs:RoseRS_3202 AMP-dependent synthetase and ligase.
  
 
 0.493
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.