Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (356 aa)    
Predicted Functional Partners:
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.938
Caur_1943
PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein; KEGG: rca:Rcas_3416 peptidase A24A domain protein.
       0.820
Caur_1942
KEGG: mgm:Mmc1_2445 nucleotidyl transferase.
       0.773
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 0.750
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
  
 0.690
Caur_0171
PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: rca:Rcas_0508 peptidoglycan glycosyltransferase.
 
   
 0.647
Caur_1901
TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: rrs:RoseRS_1948 penicillin-binding protein, 1A family.
 
   
 0.608
Caur_0115
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
  
 0.577
Caur_1298
PFAM: GCN5-related N-acetyltransferase; KEGG: rxy:Rxyl_3167 GCN5-related N-acetyltransferase.
   
    0.561
Caur_0981
PFAM: Lytic transglycosylase catalytic; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; KEGG: rca:Rcas_2690 lytic transglycosylase catalytic.
 
  
 0.560
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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