Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_1964KEGG: rrs:RoseRS_3079 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (466 aa)    
Predicted Functional Partners:
Caur_0217
KEGG: mka:MK1389 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.997
Caur_3338
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rxy:Rxyl_1091 homoserine dehydrogenase.
 
 0.996
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.961
Caur_1947
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.916
Caur_3544
PFAM: argininosuccinate synthase; KEGG: bmn:BMA10247_2224 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
 
 0.906
Caur_1922
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: rrs:RoseRS_1971 homoserine dehydrogenase.
 
 
 0.894
Caur_2355
PFAM: aminotransferase class I and II; KEGG: drm:Dred_1696 aminotransferase, class I and II.
  
 0.864
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.842
Caur_3511
Asparaginase; PFAM: peptidase T2 asparaginase 2; KEGG: rrs:RoseRS_0104 asparaginase.
     
 0.828
Caur_3645
PFAM: Asparaginase/glutaminase; KEGG: rrs:RoseRS_2187 asparaginase/glutaminase.
     
 0.828
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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