| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Caur_0217 | Caur_1966 | Caur_0217 | Caur_1966 | KEGG: mka:MK1389 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.460 |
| Caur_0217 | Caur_1967 | Caur_0217 | Caur_1967 | KEGG: mka:MK1389 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | PFAM: dihydrodipicolinate synthetase; KEGG: rrs:RoseRS_3604 dihydrodipicolinate synthetase; Belongs to the DapA family. | 0.963 |
| Caur_0217 | aroB | Caur_0217 | Caur_2103 | KEGG: mka:MK1389 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.517 |
| Caur_0217 | proA | Caur_0217 | Caur_1616 | KEGG: mka:MK1389 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.406 |
| Caur_0698 | Caur_1827 | Caur_0698 | Caur_1827 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; KEGG: rrs:RoseRS_4614 transketolase; Belongs to the transketolase family. | 0.846 |
| Caur_0698 | Caur_1966 | Caur_0698 | Caur_1966 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.920 |
| Caur_0698 | Caur_2229 | Caur_0698 | Caur_2229 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | KEGG: rca:Rcas_3120 phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA. | 0.903 |
| Caur_0698 | Caur_2517 | Caur_0698 | Caur_2517 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | PFAM: oxidoreductase domain protein; Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: rrs:RoseRS_2023 prephenate dehydrogenase. | 0.580 |
| Caur_0698 | Caur_2803 | Caur_0698 | Caur_2803 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.811 |
| Caur_0698 | aroB | Caur_0698 | Caur_2103 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.996 |
| Caur_0698 | pheA | Caur_0698 | Caur_0167 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: rrs:RoseRS_1964 prephenate dehydratase. | 0.925 |
| Caur_1827 | Caur_0698 | Caur_1827 | Caur_0698 | TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; KEGG: rrs:RoseRS_4614 transketolase; Belongs to the transketolase family. | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.846 |
| Caur_1827 | Caur_1966 | Caur_1827 | Caur_1966 | TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; KEGG: rrs:RoseRS_4614 transketolase; Belongs to the transketolase family. | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.838 |
| Caur_1827 | Caur_2229 | Caur_1827 | Caur_2229 | TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; KEGG: rrs:RoseRS_4614 transketolase; Belongs to the transketolase family. | KEGG: rca:Rcas_3120 phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA. | 0.846 |
| Caur_1827 | Caur_2803 | Caur_1827 | Caur_2803 | TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; KEGG: rrs:RoseRS_4614 transketolase; Belongs to the transketolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.999 |
| Caur_1827 | aroB | Caur_1827 | Caur_2103 | TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; KEGG: rrs:RoseRS_4614 transketolase; Belongs to the transketolase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.611 |
| Caur_1966 | Caur_0217 | Caur_1966 | Caur_0217 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | KEGG: mka:MK1389 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.460 |
| Caur_1966 | Caur_0698 | Caur_1966 | Caur_0698 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: afw:Anae109_0367 phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.920 |
| Caur_1966 | Caur_1827 | Caur_1966 | Caur_1827 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; KEGG: rrs:RoseRS_4614 transketolase; Belongs to the transketolase family. | 0.838 |
| Caur_1966 | Caur_1967 | Caur_1966 | Caur_1967 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | PFAM: dihydrodipicolinate synthetase; KEGG: rrs:RoseRS_3604 dihydrodipicolinate synthetase; Belongs to the DapA family. | 0.572 |