Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_1971PFAM: CBS domain containing protein; Rubredoxin-type Fe(Cys)4 protein; KEGG: ace:Acel_0591 putative signal-transduction protein with CBS domains. (155 aa)    
Predicted Functional Partners:
Caur_3258
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rca:Rcas_1903 glutamate synthase (ferredoxin).
  
  
 0.605
Caur_2965
Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.585
Caur_1714
PFAM: ferric-uptake regulator; KEGG: rrs:RoseRS_1293 ferric uptake regulator, Fur family; Belongs to the Fur family.
  
  
 0.549
Caur_2080
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rca:Rcas_4052 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
  
 0.539
Caur_0981
PFAM: Lytic transglycosylase catalytic; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; KEGG: rca:Rcas_2690 lytic transglycosylase catalytic.
  
  
 0.504
Caur_0457
KEGG: rca:Rcas_0108 hypothetical protein.
  
  
 0.502
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.493
Caur_3197
PFAM: ribulose-phosphate 3-epimerase; KEGG: smd:Smed_3927 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
   
 0.493
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.438
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.433
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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