STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Caur_1973Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (331 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
Caur_1974
Dihydrolipoyllysine-residue succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: rca:Rcas_2011 dihydrolipoyllysine-residue succinyltransferase.
 0.999
Caur_1335
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; KEGG: bha:BH0776 acetoin dehydrogenase (TPP-dependent) alpha chain.
 0.995
Caur_1693
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: dehydrogenase E1 component; KEGG: gtn:GTNG_2307 2-oxoisovalerate dehydrogenase alpha subunit.
 0.995
Caur_3121
PFAM: dehydrogenase E1 component; KEGG: sus:Acid_0352 pyruvate dehydrogenase (acetyl-transferring).
 0.995
Caur_3672
PFAM: dehydrogenase E1 component; KEGG: rxy:Rxyl_2403 pyruvate dehydrogenase (lipoamide).
 0.995
Caur_1333
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: tte:TTE0188 Dihydrolipoamide acyltransferases.
 0.992
Caur_2840
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rrs:RoseRS_3003 dihydrolipoamide dehydrogenase.
 0.989
Caur_1614
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic protein domain protein; malic protein NAD-binding; KEGG: rrs:RoseRS_2286 malate dehydrogenase (oxaloacetate-decarboxylating).
   
 
 0.945
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 0.945
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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