STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_1974Dihydrolipoyllysine-residue succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: rca:Rcas_2011 dihydrolipoyllysine-residue succinyltransferase. (450 aa)    
Predicted Functional Partners:
Caur_1973
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
Caur_2840
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rrs:RoseRS_3003 dihydrolipoamide dehydrogenase.
 0.999
SucA
2-oxoglutarate dehydrogenase, E1 subunit; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
 0.999
Caur_0170
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: nfa:nfa9670 putative dihydrolipoamide dehydrogenase.
 0.998
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.994
Caur_3121
PFAM: dehydrogenase E1 component; KEGG: sus:Acid_0352 pyruvate dehydrogenase (acetyl-transferring).
 0.987
Caur_1334
PFAM: Transketolase central region; Transketolase domain protein; KEGG: bpu:BPUM_1172 pyruvate dehydrogenase (acetyl-transferring) E1 component beta subunit.
 0.983
Caur_2805
PFAM: Transketolase central region; Transketolase domain protein; KEGG: rrs:RoseRS_2952 transketolase, central region.
  
 0.980
Caur_3671
PFAM: Transketolase central region; Transketolase domain protein; KEGG: btl:BALH_2493 acetoin dehydrogenase (TPP-dependent) E1 component beta subunit.
 0.980
Caur_3122
PFAM: Transketolase central region; Transketolase domain protein; KEGG: sus:Acid_0353 transketolase, central region.
 0.979
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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