node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Caur_0308 | clpB | Caur_0308 | Caur_3126 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.575 |
Caur_0308 | clpP | Caur_0308 | Caur_1527 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.415 |
Caur_0308 | clpP-2 | Caur_0308 | Caur_2818 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.415 |
Caur_0308 | dnaK | Caur_0308 | Caur_2074 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
Caur_0308 | dnaK-2 | Caur_0308 | Caur_2250 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
Caur_0308 | groL1 | Caur_0308 | Caur_2736 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.750 |
Caur_0308 | grpE | Caur_0308 | Caur_2075 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.939 |
Caur_0308 | hrcA | Caur_0308 | Caur_2076 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.720 |
Caur_1835 | clpB | Caur_1835 | Caur_3126 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.719 |
Caur_1835 | clpP | Caur_1835 | Caur_1527 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.485 |
Caur_1835 | clpP-2 | Caur_1835 | Caur_2818 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.485 |
Caur_1835 | dnaK | Caur_1835 | Caur_2074 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.975 |
Caur_1835 | dnaK-2 | Caur_1835 | Caur_2250 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.975 |
Caur_1835 | groL1 | Caur_1835 | Caur_2736 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.751 |
Caur_1835 | grpE | Caur_1835 | Caur_2075 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.856 |
Caur_1835 | hrcA | Caur_1835 | Caur_2076 | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.764 |
clpB | Caur_0308 | Caur_3126 | Caur_0308 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rrs:RoseRS_3094 chaperone DnaJ domain protein. | 0.575 |
clpB | Caur_1835 | Caur_3126 | Caur_1835 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rrs:RoseRS_2600 protein kinase. | 0.719 |
clpB | clpP | Caur_3126 | Caur_1527 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.906 |
clpB | clpP-2 | Caur_3126 | Caur_2818 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.906 |