Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Caur_2134D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: rrs:RoseRS_3360 D-lactate dehydrogenase (cytochrome). (887 aa)    
Predicted Functional Partners:
Caur_2135
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: rca:Rcas_4296 protein of unknown function DUF224 cysteine-rich region domain protein.
  
 0.972
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
    
 0.942
GlpC
TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: rrs:RoseRS_3301 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
 0.928
Caur_2963
KEGG: rrs:RoseRS_1064 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family.
    
 0.914
Caur_3128
KEGG: rca:Rcas_1692 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
   
 0.914
Caur_2080
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rca:Rcas_4052 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.912
Caur_1614
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic protein domain protein; malic protein NAD-binding; KEGG: rrs:RoseRS_2286 malate dehydrogenase (oxaloacetate-decarboxylating).
  
 
 0.909
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.907
Caur_1973
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.905
Caur_2805
PFAM: Transketolase central region; Transketolase domain protein; KEGG: rrs:RoseRS_2952 transketolase, central region.
     
 0.905
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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