Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_2145TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rrs:RoseRS_3281 HAD-superfamily hydrolase, subfamily IA, variant 3. (227 aa)    
Predicted Functional Partners:
Caur_2019
Kojibiose phosphorylase; PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; KEGG: ana:all4989 hypothetical protein.
  
 0.876
Caur_1990
PFAM: peptidase M22 glycoprotease; KEGG: rrs:RoseRS_4358 peptidase M22, glycoprotease.
      0.533
Caur_3907
Hypothetical protein; KEGG: mlo:mlr3412 glucokinase.
 
    0.480
Caur_2018
Beta-phosphoglucomutase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ava:Ava_3752 HAD-superfamily hydrolase subfamily IA, variant 3.
 
  
0.450
Caur_3356
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
      0.427
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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