Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_2235PFAM: protein of unknown function DUF970; KEGG: rca:Rcas_3719 protein of unknown function DUF970. (108 aa)    
Predicted Functional Partners:
Caur_2236
KEGG: rca:Rcas_3718 hypothetical protein.
       0.786
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
    0.784
Caur_2237
PFAM: peptidase S58 DmpA; KEGG: rca:Rcas_3716 peptidase S58 DmpA.
       0.765
Caur_2233
PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: AAA ATPase; KEGG: rrs:RoseRS_3233 single-stranded nucleic acid binding R3H domain protein.
 
     0.661
Caur_2232
KEGG: rca:Rcas_3722 hypothetical protein.
       0.567
pdxT
SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.511
dacA
Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
  
   
 0.424
Caur_1576
PFAM: YbbR family protein; KEGG: rca:Rcas_3985 YbbR family protein.
  
     0.420
pdxS
Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.414
Caur_2238
PFAM: extracellular solute-binding protein family 5; KEGG: rrs:RoseRS_0093 extracellular solute-binding protein, family 5.
       0.410
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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