STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_2249PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: rrs:RoseRS_2925 amine oxidase. (405 aa)    
Predicted Functional Partners:
Caur_2699
PFAM: SNF2-related protein; helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sat:SYN_00017 superfamily II DNA/RNA helicase, SNF2 family.
    
 0.811
Caur_0342
PFAM: histone deacetylase superfamily; KEGG: rrs:RoseRS_3190 histone deacetylase superfamily.
   
 0.785
Caur_1858
PFAM: histone deacetylase superfamily; KEGG: rca:Rcas_3448 histone deacetylase superfamily.
   
 0.785
Caur_3437
PFAM: histone deacetylase superfamily; KEGG: rrs:RoseRS_3805 histone deacetylase superfamily.
   
 0.785
Caur_2639
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
  
 0.615
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.590
Caur_0954
PFAM: Aldehyde Dehydrogenase_; KEGG: mtp:Mthe_0395 betaine-aldehyde dehydrogenase.
    
 0.549
Caur_2684
PFAM: Squalene/phytoene synthase; KEGG: rrs:RoseRS_2117 squalene/phytoene synthase.
   
  
 0.475
Caur_0894
ATP-binding region ATPase domain protein; PFAM: helix-turn-helix- domain containing protein AraC type; periplasmic binding protein/LacI transcriptional regulator; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rrs:RoseRS_0204 integral membrane sensor hybrid histidine kinase.
   
  
 0.406
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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