Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_2255PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: ter:Tery_0647 adenylate/guanylate cyclase. (437 aa)    
Predicted Functional Partners:
Caur_2251
PFAM: Tetratricopeptide TPR_4; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rpe:RPE_4376 ATPase-like protein.
 
   
 0.794
Caur_3595
PFAM: cyclic nucleotide-binding; KEGG: rrs:RoseRS_3727 cyclic nucleotide-binding protein.
 
   0.793
Caur_2753
PFAM: GAF domain protein; KEGG: rca:Rcas_3177 adenylate/guanylate cyclase with GAF and PAS/PAC sensors.
 
    0.750
Caur_3246
ATPase-like protein; KEGG: rca:Rcas_2730 adenylate/guanylate cyclase with TPR repeats.
  
     0.705
Caur_2754
PAS sensor protein; KEGG: rca:Rcas_3420 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.680
Caur_1393
KEGG: sat:SYN_00175 metal-dependent hydrolase.
 
     0.665
Caur_1394
KEGG: swo:Swol_0338 beta-lactamase-like protein.
 
     0.652
Caur_1729
PFAM: GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: rca:Rcas_3527 metal dependent phosphohydrolase.
 
   0.562
Caur_1013
PFAM: cyclic nucleotide-binding; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sfu:Sfum_4027 cyclic nucleotide-binding protein.
 
 
 0.537
Caur_1532
PFAM: cyclic nucleotide-binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: rrs:RoseRS_3166 cyclic nucleotide-binding protein.
 
   0.524
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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